Vibrational resonance in a neuron–astrocyte coupled model

نویسندگان

چکیده

Recent findings have revealed that not only neurons but also astrocytes, a special type of glial cells, are major players neuronal information processing. It is now widely accepted they contribute to the regulation their microenvironment by cross-talking with via gliotransmitters. In this context, we here study phenomenon vibrational resonance in considering interaction astrocytes. Our analysis neuron–astrocyte pair reveals intracellular dynamics astrocytes can induce double effect weak signal detection performance neuron, exhibiting two distinct wells centred at different high-frequency driving amplitudes. We identify underlying mechanism behaviour, showing separated time scales neurons, and signals key factor for emergence control resonance. This article part theme issue ‘Vibrational stochastic driven nonlinear systems (part 2)’.

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ژورنال

عنوان ژورنال: Philosophical Transactions of the Royal Society A

سال: 2021

ISSN: ['1364-503X', '1471-2962']

DOI: https://doi.org/10.1098/rsta.2020.0267